Daftar Nama Tim dan Nama Pebalap MotoGP 2021

Aprilia Racing Team Gresini

• #41 Aleix Espargaro (kontrak sampai akhir 2022)
• Kandidat rider kedua: #32 Lorenzo Savadori, #38 Bradley Smith

Ducati Team

• #43 Jack Miller (2021)
• #63 Francesco Bagnaia (2022)

LCR Honda Idemitsu-Castrol

• #30 Takaaki Nakagami (2022)
• #73 Alex Marquez (2022)

Monster Energy Yamaha

• #12 Maverick Vinales (2022)
• #20 Fabio Quartararo (2022)

Petronas Yamaha SRT

• #21 Franco Morbidelli (2022)
• #46 Valentino Rossi (2021)

Pramac Racing

• #5 Johann Zarco (2021)
• #89 Jorge Martin (2022)*

Esponsorama Racing

• #10 Luca Marini (2021)*
• #23 Enea Bastianini (2021)*

Red Bull KTM Factory Racing

• #33 Brad Binder (2021)
• #88 Miguel Oliveira (2021)

Tech 3 KTM Factory Racing

• #9 Danilo Petrucci (2021)
• #27 Iker Lecuona (2021)

Repsol Honda

• #44 Pol Espargaro (2022)
• #93 Marc Marquez (2024)

Suzuki Ecstar

• #36 Joan Mir (2022)
• #42 Alex Rins (2022)